NCIt definition : A murine IgG1 anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity.
CD45 antigen, a receptor protein-tyrosine phosphatase essential for T cell development
and lymphocyte activation, is expressed on virtually all leukocytes. Apamistamab has
specificity for hematopoietic tissues and may be used in targeted immunotherapy.;