Girentuximab - CISMeF

Preferred Label : Girentuximab;

NCIt synonyms : Monoclonal Antibody G250; Chimeric Monoclonal Antibody cG250; MoAb G250; cG250; Monoclonal Antibody G-250;

NCIt definition : A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, monoclonal antibody G250 (mAb G250) may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents. (NCI05);

UNII : 539B57DFJF;

CAS number : 916138-87-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 916138-87-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Rencarex;

Molecule name : WX-G250;

Details

Origin ID

C1960;

UMLS CUI

C3536795;

Currated CISMeF NLP mapping
- girentuximab [MeSH concept]
See also inter- (CISMeF)
- G250 monoclonal antibody [MeSH concept]
- G250 monoclonal antibody [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- girentuximab [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Carbonic Anhydrase 9 [NCIt concept]

Keyword's position in hierarchy(ies) :

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