NCIt definition : A chimeric monoclonal antibody directed against G250, a cell surface antigen found
in the majority of renal cell carcinomas. Following binding, monoclonal antibody G250
(mAb G250) may be internalized by G250 antigen-expressing renal carcinoma cells; mAb
G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic
agents. (NCI05);