" /> 4-Nitroquinoline-1-Oxide - CISMeF





Preferred Label : 4-Nitroquinoline-1-Oxide;

NCIt synonyms : 4-Nitroquinoline N-oxide; 4-Nitroquinoline-1-Oxide;

NCIt related terms : 4-nitroquinoline 1-oxide; 4-NQO;

NCIt definition : A quinoline derivative with potent tumorigenic activity. 4-nitroquinoline-1-oxide (4-NQO) potentially induces DNA damage by either binding directly to DNA and disrupting replication or through the generation of reactive oxygen species (ROS). 4-NQO is also metabolized to form other mutagenic compounds, such as 8-hydroxy-2'-deoxyguanosine.;

Alternative definition : NCI-GLOSS: A substance that is used in cancer research to cause tumors in laboratory animals. This is done to test new diets, drugs, and procedures for use in cancer prevention and treatment.;

CAS number : 56-57-5;

NSC code : 19645;

ChEBI ID : CHEBI:16907;

Codes from synonyms : CDR0000367450; CDR0000367451;

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28/05/2025


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