Preferred Label : 4-Nitroquinoline-1-Oxide;
NCIt synonyms : 4-Nitroquinoline N-oxide; 4-Nitroquinoline-1-Oxide;
NCIt related terms : 4-nitroquinoline 1-oxide; 4-NQO;
NCIt definition : A quinoline derivative with potent tumorigenic activity. 4-nitroquinoline-1-oxide
(4-NQO) potentially induces DNA damage by either binding directly to DNA and disrupting
replication or through the generation of reactive oxygen species (ROS). 4-NQO is also
metabolized to form other mutagenic compounds, such as 8-hydroxy-2'-deoxyguanosine.;
Alternative definition : NCI-GLOSS: A substance that is used in cancer research to cause tumors in laboratory
animals. This is done to test new diets, drugs, and procedures for use in cancer prevention
and treatment.;
CAS number : 56-57-5;
NSC code : 19645;
ChEBI ID : CHEBI:16907;
Codes from synonyms : CDR0000367450; CDR0000367451;
Origin ID : C194;
UMLS CUI : C0000511;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
