Preferred Label : Gallium Ga 68 N188;
NCIt synonyms : Gallium Ga 68-N188; 68Ga-N188; [68Ga]N188;
NCIt definition : A radioconjugate composed of a nectin-4 (poliovirus receptor-like 4; PVRL4)-targeting
moiety, labeled with gallium Ga 68, with potential nectin-4 imaging activity during
positron emission topography (PET)/computed tomography (CT). After intravenous administration
of gallium Ga 68 N188, the nectin-4-targeting moiety selectively targets and binds
to nectin-4 expressed on tumor cells. Upon PET/CT imaging, nectin-4-expressing tumor
cells can be visualized. Nectin-4, a tumor-associated antigen (TAA) belonging to the
nectin family, is overexpressed in a variety of cancers, but has a restricted distribution
in normal tissue.;
NCI Metathesaurus CUI : CL1913099;
Origin ID : C193449;
UMLS CUI : C5785760;
Semantic type(s)
- concept_is_in_subset
- has_target
