3-Deazauridine

Preferred Label : 3-Deazauridine;

NCIt synonyms : Deazauridine; 4-hydroxy-1-(beta-D-ribopentofuranosyl)-2-pyridone; 2(1H)-pyridinone, 4-hydroxy-1-beta-D-ribofuranosyl; 3-Deazauridine;

NCIt definition : A synthetic analogue of nucleoside uridine lacking a ring nitrogen in the 3-position. 3-deazauridine inhibits cytidine synthase, thereby reducing intracellular levels of cytidine and deoxycytidine and disrupting DNA and RNA synthesis. This agent may trigger apoptosis and enhance differentiation of neoplastic cells.(NCI04);

UNII : 263CU738ZY;

InChIKey : CBOKZNLSFMZJJA-PEBGCTIMSA-N;

CAS number : 23205-42-7;

Chemical formula : C10H13NO6;

NSC code : 126849;

Codes from synonyms : NSC0126849;

Details

Origin ID

C193;

UMLS CUI

C0000399;

Currated CISMeF NLP mapping
- 3-Deazauridine [MeSH Descriptor]
- 3-Deazauridine [MeSH concept]
- 4-hydroxy-1-.beta.-d-ribofuranosyl-2(1h)-pyridone [Substance BNPC]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 3-Deazauridine [MeSH concept]
- 3-Deazauridine [MeSH Descriptor]
- 4-hydroxy-1-.beta.-d-ribofuranosyl-2(1h)-pyridone [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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