Preferred Label : Neoantigen srRNA Vaccine JCXH-212;
NCIt synonyms : Vaccine JCXH-212;
NCIt definition : A cancer vaccine consisting of self-replicating RNA (srRNA) encoding a patient's tumor-specific
neoantigens, with potential immunomodulatory and antineoplastic activities. Upon administration
of neoantigen srRNA vaccine JCXH-212, the srRNA is taken up by and translated into
the neoantigens in the patient's antigen-presenting cells (APCs), primarily dendritic
cells (DCs), and presented by major histocompatibility complex (MHC) molecules on
the surface of the APCs. This may activate tumor antigen-specific T-cells to kill
cancer cells expressing these neoantigens.;
Molecule name : JCXH 212; JCXH-212;
NCI Metathesaurus CUI : CL1912846;
Origin ID : C192815;
UMLS CUI : C5785438;
Semantic type(s)
- concept_is_in_subset
