Preferred Label : Dynemicin;
NCIt definition : An antitumor antibiotic of the enediyne class. It has demonstrated high DNA cleavage
activity in the presence of NADPH, antimicrobial and tumor growth-inhibiting properties.
Dynemicin recognizes and cleaves conformationally flexible regions of DNA. It attacks
bases at 3'-side of purine residues such as 5'-AG, 5'-AT, and 5'-GC sequences. (NCI);
Origin ID : C1928;
UMLS CUI : C1512097;
Semantic type(s)
- Validated automatic mappings to BTNT
- concept_is_in_subset
