Preferred Label : NOS Enhancer BZ371A;
NCIt synonyms : NO Synthase Enhancer BZ371A; Nitric Oxide Synthase Enhancer BZ371A;
NCIt related terms : BZ-371A;
NCIt definition : A synthetic peptide and nitric oxide synthase (NOS) enhancer, with potential vasodilating
and anti-inflammatory activities. Upon topical application, NOS enhancer BZ371A induces
local expression of NOS, thereby increasing endogenous NO production and NO level.
This may result in vasodilation and penile erection when BZ371A is topically applied
to the genital area. BZ371A may also be topically applied to other areas such as the
eye and the skin for the treatment of glaucoma and various skin conditions through
its vasodilating and anti-inflammatory actions. Nitric oxide is an important intercellular
signaling molecule that acts as a vasodilator and an immune and inflammatory mediator.;
UNII : 9FZY7W5UNA;
Molecule name : BZ-371A; BZ 371A;
NCI Metathesaurus CUI : CL1912592;
Origin ID : C192650;
UMLS CUI : C5785353;
Semantic type(s)
- concept_is_in_subset
