Preferred Label : 4-Hydroxy-1-(3-Pyridyl)-1-Butanone;
NCIt synonyms : 4-(3-pyridyl)-4-oxobutanol; HPB; 4-Oxo-4-(3-pyridyl)-1-butanol; 4-Hydroxy-1-(pyridin-3-yl)butan-1-one; 1-Butanone, 4-hydroxy-1-(3-pyridinyl)-; 4-HPB; 4-Hydroxy-1-(3-pyridinyl)-1-butanone; 4-Hydroxy-1-pyridin-3-ylbutan-1-one;
NCIt definition : An analog of nicotinic acid with a hydroxy butyl ketone substituted for the carboxylic
acid. 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB or 4-HPB) is formed upon hydrolysis
of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine
(NNN)-containing DNA and protein adducts. Detection of HPB in certain tissue or cellular
samples can be indicative of exposure to tobacco-, tobacco-containing products and
the tobacco-specific carcinogenic nitrosamines NNK and NNN.;
UNII : Z79CGY64XC;
CAS number : 59578-62-0;
Chemical formula : C9H11NO2;
NCI Metathesaurus CUI : CL1905542;
ChEBI ID : CHEBI:82563;
Origin ID : C192185;
UMLS CUI : C0167348;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
