" /> Mesna - CISMeF





Preferred Label : Mesna;

NCIt synonyms : Sodium 2-Mercaptoethanesulphonate; Mercaptoethanesulfonate; Sodium 2-Mercaptoethane Sulfonate; Mercaptoethane Sulfonate; Mesnum; 2-Mercaptoethanesulfonic Acid Sodium Salt;

NCIt related terms : Mucofluid; Mistabronco; Uromitexan; 2-Mercaptoethanesulfonate, Sodium Salt;

NCIt definition : A sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. (NCI04);

Alternative definition : NCI-GLOSS: A drug that helps protect the kidneys and bladder from the toxic effects of anticancer drugs such as ifosfamide and cyclophosphamide.;

UNII : NR7O1405Q9;

InChIKey : XOGTZOOQQBDUSI-UHFFFAOYSA-M;

CAS number : 19767-45-4;

Drug name : Filesna; Mucolene; Mistabron; Ausobronc; Mucofluid; Mexan; Mistabronco; Ziken; Mitexan; Mesnex; Mesnil; Uromitexan;

Molecule name : UCB 3983; D-7093;

Chemical formula : C2H5O3S2.Na;

NSC code : 113891;

Codes from synonyms : CDR0000045257; 01550; NSC0113891; 328;

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07/05/2025


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