Preferred Label : Anti-CD33 CAR T-cells;
NCIt synonyms : CD33-CAR T Cells; Anti-CD33 CAR-T Cells; Anti-CD33 CAR T Cells;
NCIt definition : A preparation of T-lymphocytes that have been genetically modified to express a chimeric
antigen receptor (CAR) specific for the CD33 antigen, with potential immunomodulating
and antineoplastic activities. Upon administration, anti-CD33 CAR T-cells specifically
recognize and kill CD33-expressing tumor cells. CD33 is expressed on normal non-pluripotent
hematopoietic stem cells and is overexpressed on myeloid leukemia cells.;
NCI Metathesaurus CUI : CL1905196;
Origin ID : C191739;
UMLS CUI : C5784699;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
