Invasive Bladder Poorly Differentiated Urothelial Carcinoma

Preferred Label : Invasive Bladder Poorly Differentiated Urothelial Carcinoma;

NCIt synonyms : Bladder Poorly Differentiated Urothelial Carcinoma;

NCIt definition : Invasive bladder urothelial carcinoma that lacks the morphological features indicating urothelial origin. Immunohistochemical studies are required to demonstrate the urothelial lineage in these tumors.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1905204;

Details

Origin ID

C191731;

UMLS CUI

C5784692;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Dysuria [NCIt concept]
- Hematuria [NCIt concept]
- Urinary Frequency [NCIt concept]
Excludes anatomical site(s)
- Urethra [NCIt concept]
Has associated anatomic sites
- Bladder [NCIt concept]
- Genitourinary System [NCIt concept]
- Urinary System [NCIt concept]
- Urinary Tract [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mesenchymal Differentiation [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Transitional Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Transitional Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Poorly Differentiated Lesion [NCIt concept]
disease_has_normal_cell_origin
- Bladder Urothelial Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Urothelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Bladder Urothelium [NCIt concept]
- Epithelial Tissue [NCIt concept]
- Urothelium [NCIt concept]
disease_has_primary_anatomic_site
- Bladder [NCIt concept]
- Genitourinary System [NCIt concept]
- Urinary System [NCIt concept]
- Urinary Tract [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 17q [NCIt concept]
- Gain of Chromosome 1q [NCIt concept]
- Gain of Chromosome 5p [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Loss of Chromosome 10q [NCIt concept]
- Loss of Chromosome 11p [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 2q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
- Loss of Chromosome 8p [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
- Loss of Chromosome 9q [NCIt concept]
- Loss of Chromosome Y [NCIt concept]
disease_may_have_molecular_abnormality
- ARID1A Gene Mutation [NCIt concept]
- CDKN1A Gene Mutation [NCIt concept]
- CDKN2A Gene Mutation [NCIt concept]
- CREBBP Gene Mutation [NCIt concept]
- EP300 Gene Mutation [NCIt concept]
- ERBB2 Gene Mutation [NCIt concept]
- ERBB3 Gene Mutation [NCIt concept]
- FGFR3 Gene Mutation [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- KDM6A Gene Mutation [NCIt concept]
- KMT2C Gene Mutation [NCIt concept]
- KMT2D Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- MLL Gene Mutation [NCIt concept]
- PIK3CA Gene Mutation [NCIt concept]
- RB1 Gene Mutation [NCIt concept]
- TERT Promoter Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]
- TSC1 Gene Mutation [NCIt concept]

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