Preferred Label : Postural Orthostatic Tachycardia Syndrome Associated with Post-Acute Sequelae of SARS-CoV-2
Infection;
NCIt synonyms : PASC Postural Orthostatic Tachycardia Syndrome; Post-Acute Sequelae of COVID-19 Postural Orthostatic Tachycardia Syndrome;
NCIt related terms : PASC POTS;
NCIt definition : Postural orthostatic tachycardia syndrome (POTS) that started during probable or confirmed
acute COVID-19 and persisted at least three months after the initial diagnosis of
COVID-19.;
Alternative definition : ACC/AHA: PASC POTS is a clinical syndrome that started during probable or confirmed
acute COVID-19 and lasts greater than or equal to 3 mo. POTS is defined as 1) sustained
heart rate increment greater than or equal to 30 bpm within 10 min of standing or
head-up tilt (for individuals who are age 12-19 y, the required heart rate increment
is greater than or equal to 40 bpm); 2) absence of orthostatic hypotension (i.e.,
no sustained systolic blood pressure drop of greater than or equal to 20 mm Hg); 3)
frequent symptoms of orthostatic intolerance during standing, with rapid improvement
upon return to a supine position. Symptoms may include lightheadedness, palpitations,
tremulousness, generalized weakness, blurred vision, and fatigue; 4) duration of symptoms
for at least 3 mo; and 5) absence of other conditions explaining sinus tachycardia
such as anorexia nervosa, primary anxiety disorders, hyperventilation, anemia, fever,
pain, infection, dehydration, hyperthyroidism, pheochromocytoma, use of cardioactive
drugs (e.g., sympathomimetics, anticholinergics) or severe deconditioning caused by
prolonged bed rest.;
NCI Metathesaurus CUI : CL1904938;
Origin ID : C191603;
UMLS CUI : C5784606;
Semantic type(s)
concept_is_in_subset