Preferred Label : Personalized Neoantigen Upper Gastrointestinal Tract Cancer Vaccine;
NCIt synonyms : Personalized Neoantigen Upper GI Tract Cancer Vaccine;
NCIt definition : A personalized upper gastrointestinal (GI) tract cancer vaccine consisting of multiple
patient-specific tumor-derived neoantigens, which are identified based on patient-specific
tumor mutations obtained from the individual's tumor, with potential immunostimulatory
and antineoplastic activities. Upon administration, the personalized neoantigen upper
GI tract cancer vaccine stimulates the host immune system to mount a cytotoxic T lymphocyte
(CTL) response against tumor cells expressing the neoantigens, which results in tumor
cell lysis.;
NCI Metathesaurus CUI : CL1904894;
Origin ID : C191201;
UMLS CUI : C5784293;
Semantic type(s)
concept_is_in_subset