Famtozinameran

Preferred Label : Famtozinameran;

NCIt synonyms : BNT162b2 Omicron BA.4/BA.5 mRNA; BNT162b2 Omicron BA.4/BA.5;

NCIt definition : A formulation consisting of lipid nanoparticle (LNP) encapsulating a nucleoside modified messenger RNA (modRNA) encoding an optimized form of the full-length viral spike (S) glycoprotein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant lineages BA.4 and BA.5 (Omicron BA.4/BA.5), with potential immunizing and anti-COVID-19 activities. Upon administration of famtozinameran, the LNPs bind to the plasma membrane of nearby cells and release SARS-CoV-2 S protein mRNA into the cells. The mRNA is then translated by the cellular protein translation machinery to produce SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection.;

UNII : JSV288Q5CV;

NCI Metathesaurus CUI : CL1799336;

Details

Origin ID

C190751;

UMLS CUI

C5699493;

Currated CISMeF NLP mapping
- famtozinameran [MeSH concept]
- famtozinameran [MeSH Supplementary Concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- famtozinameran [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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