Preferred Label : Allogeneic Umbilical Cord Blood-derived CXCR4-enriched T-regulatory Cells CK0804;
NCIt synonyms : Allogeneic UCB-derived CXCR4-enriched Tregs CK0804;
NCIt definition : A preparation of allogeneic T-regulatory cells (Tregs) derived from umbilical cord
blood (UCB) and enriched with C-X-C chemokine receptor type 4 (CXCR4), with potential
immunomodulatory activity. Upon administration, allogeneic UCB-derived CXCR4-enriched
Tregs CK0804 may promote immunologic homeostasis and modulate immune responses. CXCR4
enrichment promotes the traffic of the Tregs to the bone marrow and its retainment
in the bone marrow, as bone marrow expresses the CXCR4 ligand stromal cell-derived
factor 1 (CXCL12).;
Molecule name : CK 0804; CK-0804;
NCI Metathesaurus CUI : CL1799119;
Origin ID : C190649;
UMLS CUI : C5783836;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
