HLA Class II Histocompatibility Antigen, DR Beta 3 Chain

Preferred Label : HLA Class II Histocompatibility Antigen, DR Beta 3 Chain;

NCIt synonyms : HLA-DRB3; MHC Class II Antigen DRB3;

NCIt definition : HLA class II histocompatibility antigen, DR beta 3 chain (266 aa, 30 kDa) is encoded by the human HLA-DRB3 gene. This protein is involved in the presentation of antigenic peptides derived from extracellular proteins for recognition by alpha-beta T cell receptor (TCR) expressing T-lymphocytes.;

NCI Metathesaurus CUI : CL1799256;

Details

Origin ID

C190571;

UMLS CUI

C5780933;

Automatic exact mappings (from CISMeF team)
- HLA-DRB3 [LOINC component]
- HLA-DRB3 chains [MeSH Descriptor]
- Major histocompatibility complex, class II, dr beta-3 [OMIM gene]
OMIM relation
- Major histocompatibility complex, class II, dr beta-3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
gene_encodes_gene_product
- HLA-DRB3 Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- MHC Class II Gene [NCIt concept]
gene_product_expressed_in_tissue
- CD4-Positive T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- HLA Complex [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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