KRT6B wt Allele

Preferred Label : KRT6B wt Allele;

NCIt synonyms : CK-6B; Keratin, Type II Cytoskeletal 6B Gene; KRTL1; CK6B; KB10; K6B; Keratin 6B wt Allele; Keratin 6B, Type II Gene; PC2; PC4; Keratin, Epidermal, Type II, K6B Gene; Keratin-Like 1 (A Type II Keratin Sequence) Gene; Cytokeratin 6B Gene;

NCIt definition : Human KRT6B wild-type allele is located in the vicinity of 12q13.13 and is approximately 5 kb in length. This allele, which encodes keratin, type II cytoskeletal 6B protein, is involved in wound healing by keratinocytes. Mutation of the gene is associated with pachyonychia congenita 4.;

NCI Metathesaurus CUI : CL1799037;

GenBank Accession Number : BC034535;

Details

Origin ID

C190246;

UMLS CUI

C5780943;

Automatic exact mappings (from CISMeF team)
- Chromobox 4 [OMIM gene]
- Interferon-related developmental regulator 1 [OMIM gene]
- Keratin 6b, type II [OMIM gene]
- PC2 (body structure) [SNOMED CT concept]
- PC4 (body structure) [SNOMED CT concept]
- Pachyonychia congenita 2 [OMIM Phenotype]
- Pachyonychia congenita 4 [OMIM Phenotype]
- Polycystin 2 [OMIM gene]
- Proprotein convertase 2 (substance) [SNOMED CT concept]
- Proprotein convertase, subtilisin/kexin-type, 2 [OMIM gene]
- Sub1 regulator of transcription [OMIM gene]
- interferon related developmental regulator 1 [ORDO Gene]
OMIM relation
- Keratin 6b, type II [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q13.13 [NCIt concept]
gene_plays_role_in_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Histogenic Process [NCIt concept]
- Keratinization [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Regulation of Cell Shape [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients