Preferred Label : Tri-specific NK Cell Engager CC-92328;
NCIt synonyms : Tri-specific NK Cell Engager Therapeutic Agent CC-92328; TriNKET CC-92328;
NCIt definition : A tri-specific natural killer (NK) cell engager, with potential immunomodulating and
antineoplastic activities. Upon administration, the tri-specific NK cell engager CC-92328
binds to as of yet unelucidated proteins expressed on both cancer cells and NK cells,
thereby bringing cancer cells and NK cells together. This stimulates the NKs and allows
for NK-mediated cancer cell killing. In addition, the NKs activate T- and B-cells,
and enhance a cytotoxic T-lymphocyte (CTL) immune response against cancer cells.;
Molecule name : CC-92328; CC 92328;
NCI Metathesaurus CUI : CL1798737;
Origin ID : C190202;
UMLS CUI : C5783561;
Semantic type(s)
- concept_is_in_subset
