Preferred Label : Cisplatin Micelle Formulation HA132;
NCIt synonyms : Cisplatin Micelle HA132;
NCIt definition : A micelle formulation containing the inorganic platinum agent cisplatin, with potential
antineoplastic activity. Upon administration, cisplatin forms highly reactive, charged,
platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA
inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links.
These cross-links result in apoptosis and growth inhibition of tumor cells.;
Molecule name : HA-132; HA 132;
NCI Metathesaurus CUI : CL1798782;
Origin ID : C190122;
UMLS CUI : C5783510;
Semantic type(s)
- concept_is_in_subset
