Preferred Label : Monoclonal Antibody DR-01;
NCIt definition : A human non-fucosylated immunoglobulin G1 (IgG1) monoclonal antibody directed against
an as of yet undisclosed cell surface receptor expressed on cytotoxic cells, with
potential immunomodulatory and antineoplastic activities. Upon administration, monoclonal
antibody DR-01 binds to the as of yet undisclosed cell surface receptor expressed
on cytotoxic cells and induces antibody-dependent cellular cytotoxicity (ADCC) against
these cytotoxic cells. This may reduce tumor cell proliferation of certain leukemias
and lymphomas, and modulate immune responses in certain autoimmune conditions.;
Molecule name : DR 01; DR-01;
NCI Metathesaurus CUI : CL1798774;
Origin ID : C190114;
UMLS CUI : C5783502;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
