Preferred Label : Fluorine F 18-FETrp;
NCIt synonyms : 1-L-[18F]FETrp; 1-(2-[18F]Fluoroethyl)-L-tryptophan; L-[18F]FETrp; L-Tryptophan, 1-(2-(fluoro-18F)ethyl)-; 18F-FETrp;
NCIt related terms : 1-(2-(FLUORO-18F)ETHYL)-L-TRYPTOPHAN;
NCIt definition : A radioconjugate containing an analog of tryptophan, fluoroethyl-tryptophan (FETrp),
labeled with the positron-emitting radioisotope fluorine F 18, with potential imaging
applications upon positron emitting tomography (PET). Upon administration, fluorine
F 18-FETrp is taken up by and accumulates in tumor cells. This may allow for the visualization
of tumors upon PET. The immunosuppressive kynurenine pathway present in tumor cells
leads to abnormal tryptophan metabolism and increased uptake of tryptophan by tumor
cells.;
UNII : 6LM9298FSC;
CAS number : 1323265-05-9;
NCI Metathesaurus CUI : CL1798850;
Origin ID : C190018;
UMLS CUI : C5783451;
Semantic type(s)
- concept_is_in_subset
