Preferred Label : Elasomeran/Imelasomeran;
NCIt synonyms : Original/Omicron BA.1 Bivalent COVID-19 Booster Vaccine mRNA-1273.214;
NCIt definition : A bivalent booster vaccine consisting of elasomeran, a lipid nanoparticle (LNP) encapsulating
a messenger RNA (mRNA) encoding the prefusion stabilized spike (S) protein of the
SARS-CoV-2 Wuhan-Hu-1 strain (original), and imelasomeran, a LNP encapsulating mRNA
encoding the prefusion stabilized S-protein of the SARS-CoV-2 Omicron variant B.1.1.529,
with potential immunizing activity against SARS-CoV-2. Upon administration of elasomeran/imelasomeran,
the LNP binds to the plasma membrane of cells and releases the mRNA into the cells.
The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This
may activate both humoral and cellular immune responses which may result in protection
against SARS-CoV-2 infection.;
Molecule name : mRNA-1273.214; mRNA 1273.214;
NCI Metathesaurus CUI : CL1798631;
Origin ID : C189803;
UMLS CUI : C5708757;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
