Activating MAP2K2 Gene Mutation

Preferred Label : Activating MAP2K2 Gene Mutation;

NCIt synonyms : Gain of Function MAP2K2 Mutation; Activating PRKMK2 Gene Mutation; Gain of Function MAP2K2 Gene Mutation; Activating Mitogen-Activated Protein Kinase Kinase 2 Gene Mutation; MAP2K2 Activating Mutation; MAP2K2 Gain of Function Gene Mutation; Activating MAPKK2 Gene Mutation; Activating MAP2K2 Mutation; Activating MEK2 Gene Mutation; MAP2K2 Gain of Function Mutation; MAP2K2 Activating Gene Mutation; Activating MKK2 Gene Mutation;

NCIt definition : A change in the nucleotide sequence of the MAP2K2 gene that results in constitutive activation of both dual specificity mitogen-activated protein kinase kinase 2 and its downstream signaling pathways.;

NCI Metathesaurus CUI : CL1794533;

Details

Origin ID

C189345;

UMLS CUI

C5708392;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- MAP2K2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients