Preferred Label : Dolastatin Compound;
NCIt synonyms : Dolastatins;
NCIt definition : Any of a class of natural peptides originally isolated from the marine mollusk Dolabella
auricularia that bind to tubulin at the vinca/peptide region, thereby inhibiting microtubule
assembly and leading to cell cycle arrest and/or apoptosis.;
Origin ID : C1893;
UMLS CUI : C1512030;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
