Activating MAP2K1 Gene Mutation

Preferred Label : Activating MAP2K1 Gene Mutation;

NCIt synonyms : Gain of Function MAP2K1 Mutation; Activating PRKMK1 Gene Mutation; Gain of Function MAP2K1 Gene Mutation; Activating Mitogen-Activated Protein Kinase Kinase 1 Gene Mutation; MAP2K1 Activating Mutation; MAP2K1 Gain of Function Gene Mutation; Activating MAPKK1 Gene Mutation; Activating MAP2K1 Mutation; Activating MEK1 Gene Mutation; MAP2K1 Gain of Function Mutation; MAP2K1 Activating Gene Mutation; Activating MKK1 Gene Mutation;

NCIt definition : A change in the nucleotide sequence of the MAP2K1 gene that results in constitutive activation of both dual specificity mitogen-activated protein kinase kinase 1 and its downstream signaling pathways.;

NCI Metathesaurus CUI : CL1794195;

Details

Origin ID

C189228;

UMLS CUI

C5708323;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- MAP2K1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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