Preferred Label : Efocipegtrutide;
NCIt definition : A long-acting glucagon/gastric inhibitory peptide (GIP)/glucagon-like peptide-1 (GLP-1)
triple receptor agonist conjugated with constant region of human immunoglobulin via
a non-peptidyl flexible linker, with potential antihyperglycemic, anti-inflammatory
and anti-fibrotic activities. Upon administration, efocipegtrutide binds to and activates
multiple incretin receptors, including glucagon receptor (GCGR), GIP receptor (GIPR)
and GLP-1 receptor (GLP-1R), which may decrease liver fat accumulation, inflammation
and fibrogenesis, and normalize blood glucose levels.;
UNII : TUI1MDD9F6;
CAS number : 2513399-19-2;
Molecule name : HM-15211; HM 15211;
NCI Metathesaurus CUI : CL1793826;
Origin ID : C188633;
UMLS CUI : C5707932;
Semantic type(s)
- concept_is_in_subset
