Preferred Label : Anti-CEA CAR T Cells;
NCIt synonyms : Anti-CEA-CAR T-lymphocytes; Anti-CEA CAR-T Cells; Anti-CEA CAR T-cells; CEA CAR-T Cells;
NCIt definition : A preparation of T-lymphocytes engineered to express a chimeric antigen receptor (CAR)
specific for the tumor-associated antigen (TAA) human carcinoembryonic antigen (CEA),
with potential immunostimulating and antineoplastic activities. Upon administration,
anti-CEA CAR T cells specifically recognize and induce selective toxicity in CEA-expressing
tumor cells. CEA, a member of the CEA family of proteins, plays a key role in cell
migration, cell invasion and cell adhesion, and is overexpressed by a variety of cancer
types.;
NCI Metathesaurus CUI : CL1793615;
Origin ID : C188356;
UMLS CUI : C5707721;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
