Preferred Label : H3Y2 wt Allele;
NCIt synonyms : H3.Y Histone 2 wt Allele; H3.X; Histone Cluster 2, H3d Pseudogene Gene; H3.Y.2; LOC340096; H3 Histone, Family 3B (H3.3B) Pseudogene Gene; H3 Histone, Family 3B Pseudogene Gene;
NCIt definition : Human H3Y2 wild-type allele is located in the vicinity of 5p15.1 and is approximately
1 kb in length. This allele, which encodes histone H3.X protein, may play a role in
nucleosome structure and transcriptional regulation.;
NCIt note : J Cell Biol. 2010;190:777-91 reports the primate-specific expression of a histone
H3.X protein in normal testis, fetal brain, cerebral cortex, cerebellum and hippocampus.
H3.X was also reported to be expressed in cancerous bone, breast and lung tissue.;
NCI Metathesaurus CUI : CL1793120;
GenBank Accession Number : NM_001371919;
PubMed : 20819935;
Origin ID : C188200;
UMLS CUI : C5702692;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
