" /> Motexafin Gadolinium - CISMeF





Preferred Label : Motexafin Gadolinium;

NCIt synonyms : Gadolinium Texaphyrin; Gd (III) Texaphryin; Gd-Tex;

NCIt definition : A synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating reactive oxygen species (ROS) intracellularly and lowering the tumor cell apoptotic threshold to ionizing radiation and chemotherapy. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells. It is a type of metalloporphyrin complex.;

UNII : 6433A42F4F;

InChIKey : KHDBHVDCUGRVLA-IOYKFIIZSA-L;

CAS number : 156436-89-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 156436-89-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Xcytrin;

Molecule name : PCI-0120; API-GP3;

Chemical formula : C48H66N5O10.2C2H3O2.Gd;

NSC code : 695238;

ChEBI ID : CHEBI:50162; CHEBI:50161;

Codes from synonyms : CDR0000413947; CDR0000045468;

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12/05/2024


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