Thyroblastoma - CISMeF

Preferred Label : Thyroblastoma;

NCIt synonyms : Thyroid Gland Malignant Teratoma; Thyroid Gland Immature Teratoma; Thyroid Gland Teratocarcinosarcoma; Thyroid Gland Malignant Teratoid Tumor; Thyroid Gland Carcinosarcoma;

NCIt definition : A high-grade, rapidly growing malignant embryonal neoplasm that arises from the thyroid gland. It is characterized by the presence of primitive follicular-like structures surrounded by primitive small cells and primitive spindle cell mesenchymal stroma. It is associated with DICER1 gene mutations. The prognosis is poor.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1792883;

Details

Origin ID

C187995;

UMLS CUI

C5703450;

Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_normal_tissue_origin
- Germinal Layer [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Small Undifferentiated Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
disease_has_finding
- Aggressive Clinical Course [NCIt concept]
- Follicular Structures Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Primitive Mesenchymal Stroma Formation [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_molecular_abnormality
- DICER1 Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- Embryonic Cell [NCIt concept]
disease_has_normal_tissue_origin
- Embryonic Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- DICER1 Gene [NCIt concept]
pathogenesis_of_disease_involves_gene
- DICER1 Gene [NCIt concept]
- DICER1 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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