High Grade Follicular Cell-Derived Non-Anaplastic Thyroid Gland Carcinoma

Preferred Label : High Grade Follicular Cell-Derived Non-Anaplastic Thyroid Gland Carcinoma;

NCIt synonyms : Follicular-Derived Thyroid Gland Carcinoma, High-Grade; Follicular-Derived Thyroid Gland Carcinoma, High Grade; High-Grade Follicular Cell-Derived Non-Anaplastic Thyroid Gland Carcinoma;

NCIt definition : A thyroid gland carcinoma that arises from follicular cells and is characterized by the presence of high mitotic activity and necrotic changes in the absence of anaplastic histological features. This category includes poorly differentiated thyroid gland carcinoma and differentiated high-grade thyroid gland carcinoma.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1792422;

Details

Origin ID

C187645;

UMLS CUI

C5707271;

Disease excludes abnormal cell
- Anaplastic Carcinoma Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Cold Nodule [NCIt concept]
Has associated anatomic sites
- Endocrine Gland [NCIt concept]
- Endocrine System [NCIt concept]
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Thyroid Gland Follicular Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Grade Lesion [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Necrotic Change [NCIt concept]
- Thyroglobulin-Positive Neoplastic Cells Present [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Thyroid Gland Follicular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
disease_has_primary_anatomic_site
- Endocrine Gland [NCIt concept]
- Endocrine System [NCIt concept]
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF NP_004324.2:p.V600E [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]
- TERT Promoter Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

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