Thyroid Gland Follicular Carcinoma, Signet Ring Cell Variant

Preferred Label : Thyroid Gland Follicular Carcinoma, Signet Ring Cell Variant;

NCIt definition : A morphologic variant of follicular carcinoma of the thyroid gland characterized by the presence of malignant follicular cells with cytoplasmic vacuoles and eccentrically placed nuclei.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1792408;

Details

Origin ID

C187643;

UMLS CUI

C5707269;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Cold Nodule [NCIt concept]
- Follicular Structures Present [NCIt concept]
- Solid Growth Pattern [NCIt concept]
- Trabecular Pattern [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Ground Glass Nuclear Inclusion [NCIt concept]
- High Grade Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Nuclear Clearing [NCIt concept]
- Nuclear Grooves [NCIt concept]
- Nuclear Pseudoinclusion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Thyroid Gland Follicular Cell [NCIt concept]
- Malignant Thyroid Gland Follicular Signet Ring Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Encapsulated Mass [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Follicular Cell Differentiation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Thyroglobulin-Positive Neoplastic Cells Present [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Thyroid Gland Follicular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- CREB3L2/PPARG Fusion Gene [NCIt concept]
- PAX8/PPARG Fusion Gene [NCIt concept]
disease_may_have_molecular_abnormality
- DICER1 Gene Mutation [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]
- PIK3CA Gene Mutation [NCIt concept]
- PPARG Gene Rearrangement [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- TERT Promoter Mutation [NCIt concept]

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