NCIt definition : Drosophila Patched Gene (Patched Family) encodes Patched protein, an integral membrane
protein containing an SSD domain that acts as a segmentation polarity pattern receptor
for hedgehog during embryonic segmentation and during imaginal disk development. Patched
associates with smoothened protein to transduce hedgehog signal, leading to activation
of wingless, decapentaplegic, and patched. In the absence of hedgehog, patched represses
constitutive smoothened signaling through fused. (NCI);
False automatic mappings