Thyroid Gland Follicular Adenoma with Papillary Architecture

Preferred Label : Thyroid Gland Follicular Adenoma with Papillary Architecture;

NCIt synonyms : Thyroid Gland Follicular Adenoma with Papillary Hyperplasia;

NCIt definition : A benign, encapsulated thyroid gland neoplasm characterized by the presence of large follicles with intrafollicular papillary architecture. The cells lining the papillae are usually columnar. It is usually a cystic neoplasm and lacks nuclear atypia and capsular invasion. Psammoma bodies are not present. Activating TSHR mutations have been described in the majority of cases. In a small number of cases GNAS mutations have been identified.;

Neoplastic status : Benign;

NCI Metathesaurus CUI : CL1792299;

Details

Origin ID

C187261;

UMLS CUI

C5706996;

Disease excludes abnormal cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease excludes normal cell origin
- Endocrine-Stromal Cell [NCIt concept]
Disease may have findings
- Radiation Toxicity [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_cytogenetic_abnormality
- Loss of Chromosome 11q [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 14q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
- Loss of Chromosome 9q [NCIt concept]
disease_excludes_finding
- Borderline Lesion [NCIt concept]
- Capsular Invasion [NCIt concept]
- Ground Glass Nuclear Inclusion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Nuclear Atypia [NCIt concept]
- Nuclear Clearing [NCIt concept]
- Nuclear Grooves [NCIt concept]
- Nuclear Pseudoinclusion [NCIt concept]
- Psammoma Body Formation [NCIt concept]
- Tumor Vascular Invasion [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Thyroid Gland Follicular Cell [NCIt concept]
disease_has_finding
- Benign Cellular Infiltrate [NCIt concept]
- Encapsulated Mass [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Follicular Structures Present [NCIt concept]
- Monoclonal Cellular Population Present [NCIt concept]
- Neoplastic Cells with Papillary Architecture Present [NCIt concept]
- Nodular Lesion [NCIt concept]
- Thyroglobulin-Positive Neoplastic Cells Present [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Thyroid Gland Follicular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
- Thyroid Gland Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- PAX8/PPARG Fusion Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12 [NCIt concept]
- Gain of Chromosome 5 [NCIt concept]
- Loss of Chromosome 10 [NCIt concept]
- Loss of Chromosome 13 [NCIt concept]
- Loss of Chromosome 19 [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Trisomy 7 [NCIt concept]
disease_may_have_molecular_abnormality
- Activating TSHR Gene Mutation [NCIt concept]
- GNAS Gene Mutation [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]

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