Nicotinic Acetylcholine Receptor

Preferred Label : Nicotinic Acetylcholine Receptor;

NCIt synonyms : Nicotinic Receptor; nAChR;

NCIt definition : Heteropentameric transmembrane protein complexes that act as ligand-gated cation-specific channels in response to acetylcholine- and nicotine-binding. Nicotinic acetylcholine receptors are expressed in a wide varietly of cell and tissue types and are involved in neurotransmission, muscle contraction and inflammation.;

NCI Metathesaurus CUI : CL1792935;

Details

Origin ID

C187222;

UMLS CUI

C0034830;

Automatic exact mappings (from CISMeF team)
- Nicotinic acetylcholine receptor [FMA entity]
- Nicotinic receptor (substance) [SNOMED CT concept]
- acetylcholine-gated channel complex [GO term]
- acetylcholine-gated monoatomic cation-selective channel activity [GO term]
- receptors, nicotinic [MeSH Descriptor]
- receptors, nicotinic [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Nicotinic acetylcholine receptor [FMA entity]
- Nicotinic receptor (substance) [SNOMED CT concept]
- nicotinic receptor site [SNOMED Notion]
- receptors, nicotinic [MeSH Descriptor]
- receptors, nicotinic [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- Gated Ion Channel [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Ion Channel Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Muscle Contraction [NCIt concept]
- Neuronal Transmission [NCIt concept]
has_gene_product_element
- Acetylcholine Receptor Subunit Epsilon [NCIt concept]
- Neuronal Acetylcholine Receptor Subunit Alpha-3 [NCIt concept]
- Neuronal Acetylcholine Receptor Subunit Alpha-5 [NCIt concept]
- Neuronal Acetylcholine Receptor Subunit Beta-4 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients