Preferred Label : Black Seed Oil Extract Supplement;
NCIt synonyms : Thymoquinone Formula; Black Seed Oil Extract-based Supplement; Black Seed Oil Capsule; TQ Formula;
NCIt definition : An oral supplement composed of the oil extracted from the seeds of Nigella sativa,
also known as black seed or black cumin, with potential anti-oxidant, anti-inflammatory,
hepatoprotective and immunomodulatory activities. Upon administration of black seed
oil extract supplement, the main constituent thymoquinone may stimulate various cytoprotective
antioxidant enzymes. Thymoquinone may also exert anti-inflammatory activity by decreasing
the production of inflammation mediators, such as tumor necrosis factor (TNF)-alpha,
interleukin (IL) 1-beta and IL-6, and inhibiting pro-inflammatory enzymes, including
cyclooxygenase (COX). In addition, thymoquinone may modulate the activity of various
immune cells such as T-cells, B-cells, macrophages, neutrophils, natural killer (NK)
cells, and dendritic cells (DCs) in the tumor microenvironment (TME) and may enhance
anticancer immune responses.;
Molecule name : NP 101; NP-101;
NCI Metathesaurus CUI : CL1792016;
Origin ID : C187132;
UMLS CUI : C5706897;
Semantic type(s)
concept_is_in_subset