Preferred Label : Allogeneic Nicotinamide-expanded Natural Killer Cells GDA-201;
NCIt synonyms : NAM NKs GDA-201; NAM-expanded Allogeneic NK Cells GDA-201; Allogeneic NAM-expanded NK Cells GDA-201;
NCIt definition : A preparation of allogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells,
with potential cytolytic and antineoplastic activities. Upon administration, the allogeneic
NAM-expanded NK cells GDA-201 may lyse cancer cells. These cells also secrete pro-inflammatory
cytokines, which further stimulate an anti-tumor immune response. Ex-vivo treatment
with the vitamin B3 derivative NAM increases the in-vivo homing, retention and proliferation
potential of the NK cells.;
Molecule name : GDA-201; GDA 201;
NCI Metathesaurus CUI : CL1792018;
Origin ID : C187130;
UMLS CUI : C5706377;
- Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset