Preferred Label : Curcumin/Polyphenols-containing Botanical Agent APG-157;
NCIt definition : An orally bioavailable botanically-based formulation containing multiple polyphenols,
including curcumin, the polyphenol derived from the plant Curcuma longa that is also
known as turmeric, with potential anti-inflammatory, immunomodulatory and antineoplastic
activities. Upon oral administration of curcumin/polyphenols-containing botanical
agent APG-157, the curcumin and polyphenols in APG-157 may exert anti-inflammatory
activity by decreasing the production of inflammation mediators, such as interleukin
(IL) 1-beta, IL-6 and IL-8. The curcumin and polyphenols may also promote T-cell recruitment
to the tumor microenvironment (TME) and cytotoxic effects against cancer cells.;
Molecule name : APG 157; APG-157;
NCI Metathesaurus CUI : CL1792006;
Origin ID : C187126;
UMLS CUI : C5706373;
Semantic type(s)
- concept_is_in_subset
