Mature Plurihormonal PIT1 Lineage Pituitary Neuroendocrine Tumor

Preferred Label : Mature Plurihormonal PIT1 Lineage Pituitary Neuroendocrine Tumor;

NCIt synonyms : Mature Plurihormonal PIT1 Lineage PitNET/Adenoma; Mature Plurihormonal PIT1 Lineage Pituitary Neuroendocrine Tumor/Adenoma;

NCIt definition : A well-differentiated pituitary neuroendocrine tumor composed of PIT1-lineage adenohypophyseal cells with acidophilic cytoplasm, extensive immunoreactivity for growth hormone and variable immunoreactivity for TSH, prolactin, and alpha-subunit. (WHO);

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL1791989;

Details

Origin ID

C187098;

UMLS CUI

C5706894;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Base of the Skull [NCIt concept]
- Central Nervous System [NCIt concept]
- Head and Neck [NCIt concept]
- Nervous System [NCIt concept]
- Pituitary Gland [NCIt concept]
- Sellar Region [NCIt concept]
- Skull [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Adenohypophysial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Multihormonal Immunoreactivity Present [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Acidophilic Cell [NCIt concept]
- Adenohypophysial Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- PIT1-Lineage Adenohypophysial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Anterior Lobe of the Pituitary Gland [NCIt concept]
disease_mapped_to_gene
- POU1F1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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