" /> Valdecoxib - CISMeF





Preferred Label : Valdecoxib;

NCIt synonyms : 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide;

NCIt definition : A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation.;

Alternative definition : NCI-GLOSS: A substance that is being studied as a treatment for pain and other side effects of cancer therapy. It belongs to the family of drugs called COX-2 inhibitors.;

UNII : 2919279Q3W;

InChIKey : LNPDTQAFDNKSHK-UHFFFAOYSA-N;

CAS number : 181695-72-7;

Drug name : Bextra;

Molecule name : SC 65872;

Chemical formula : C16H14N2O3S;

ChEBI ID : CHEBI:63634;

Codes from synonyms : 50465; CDR0000045021;

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08/05/2025


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