CECR2 wt Allele

Preferred Label : CECR2 wt Allele;

NCIt synonyms : Cat Eye Syndrome Chromosome Region, Candidate 2 Gene; CECR2 Histone Acetyl-Lysine Reader wt Allele; KIAA1740;

NCIt definition : Human CECR2 wild-type allele is located within 22q11.1-q11.21 and is approximately 198 kb in length. This allele, which encodes cat eye syndrome critical region protein 2, plays a role in chromatin remodeling.;

NCIt note : CECR2 drives breast cancer metastasis by promoting NF-kappaB signaling and macrophage-mediated immune suppression. (Science Translational Medicine, 2022; 14:DOI: 10.1126/scitranslmed.abf5473);

NCI Metathesaurus CUI : CL1778782;

GenBank Accession Number : AF336133;

Details

Origin ID

C186605;

UMLS CUI

C5575447;

Automatic exact mappings (from CISMeF team)
- Cat eye syndrome chromosome region, candidate 2 [ORDO Gene]
- Cecr2 histone acetyl-lysine reader [OMIM gene]
OMIM relation
- Cecr2 histone acetyl-lysine reader [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]

Keyword's position in hierarchy(ies) :

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