Epipodophyllotoxin Analog GL331

Preferred Label : Epipodophyllotoxin Analog GL331;

NCIt definition : An epipodophyllotoxin analogue possessing antineoplastic properties. GL331 binds to and inhibits topoisomerase II, resulting in the accumulation of single- or double-strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death. (NCI);

Molecule name : GL331;

Details

Origin ID

C1866;

UMLS CUI

C0908996;

Automatic exact mappings (from CISMeF team)
- GL 331 [MeSH Supplementary Concept]
- GL 331 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GL 331 [MeSH Supplementary Concept]
- GL 331 [MeSH concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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