Preferred Label : Allogeneic Virus-specific T-lymphocytes R-MVST;
NCIt synonyms : Rapidly-generated Virus-specific T-cells; R-MVST; R-MVST Cells;
NCIt definition : A preparation of allogeneic T-lymphocytes generated from partially human leukocyte
antigen (HLA)-matched healthy donors or from the original allogeneic hematopoietic
stem cell transplantation (HSCT) donor, ex-vivo expanded, and specifically reactive
to viruses that may include adenovirus (AdV), cytomegalovirus (CMV), Epstein-Barr
virus (EBV) and human polyomavirus type I (BKV), with potential antiviral activity.
Upon administration, the allogeneic virus-specific T-lymphocytes R-MVST may kill AdV,
CMV, EBV and/or BKV-infected cells, and may prevent or reduce the severity of viral
infections by these pathogens.;
NCI Metathesaurus CUI : CL1778589;
Origin ID : C186371;
UMLS CUI : C5666817;
Semantic type(s)
- Cell [UMLS semantic type]
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