Preferred Label : Aclacinomycin B;
NCIt synonyms : Aclarubicin B; Antibiotic MA 144B1; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-,
methyl ester,(1R-(1-alpha,2-beta,4-beta))-;
NCIt definition : An antineoplastic oligosaccharide anthracycline antibiotic isolated from the bacterium
Streptomyces galilaeus. Aclacinomycin B intercalates into DNA and inhibits both the
topoisomerase I and II enzymes, thereby inhibiting DNA replication and ultimately,
interfering with RNA and protein synthesis.;
UNII : P8EJD9HI5K;
CAS number : 57596-79-9;
NSC code : 208735;
Codes from synonyms : NSC0208735;
Origin ID : C1861;
UMLS CUI : C0889093;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
