Diffuse Glioneuronal Tumor with Oligodendroglioma-Like Features and Nuclear Clusters - CISMeF
Diffuse Glioneuronal Tumor with Oligodendroglioma-Like Features and Nuclear ClustersNCIt concept
Preferred Label : Diffuse Glioneuronal Tumor with Oligodendroglioma-Like Features and Nuclear Clusters;
NCIt synonyms : DGONC;
NCIt definition : A provisional tumor entity described in the supratentorial brain and characterized
by a distinct DNA methylation profile and monosomy of chromosome 14. It is composed
of small to medium-sized cells showing perinuclear oligodendroglioma-like haloes,
scattered multinucleated cells, and nuclear clusters composed of large pleomorphic
nuclei. Most cases have been reported in pediatric patients.;