" /> Panitumumab - CISMeF





Preferred Label : Panitumumab;

NCIt synonyms : ABX-EGF Monoclonal Antibody; Monoclonal Antibody ABX-EGF; ABX-EGF, Clone E7.6.3; MoAb ABX-EGF; MoAb E7.6.3; Monoclonal Antibody E7.6.3; Human IgG2K Monoclonal Antibody;

NCIt related terms : ABX-EGF; Vectibix;

NCIt definition : A human IgG2kappa monoclonal antibody specific for the epidermal growth factor receptor (EGFR). Monoclonal antibody E7.6.3 binds to the EGFR, blocking the binding of epidermal growth factor and transforming growth factor alpha to EGFR-expressing cancer cells and ultimately inhibiting EGFR-dependent cell activation and proliferation. (NCI);

Alternative definition : NCI-GLOSS: A human monoclonal antibody that is being used to treat colorectal cancer that has spread to other parts of the body. It is used in patients whose disease has not gotten better during or after treatment with other anticancer drugs. It is also being studied in the treatment of other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. ABX-EGF binds to the epidermal growth factor receptor (EGFR) and may block tumor cell growth.;

UNII : 6A901E312A;

CAS number : 339177-26-3;

Drug name : Vectibix;

Molecule name : E7.6.3;

Codes from synonyms : CDR0000302450; CDR0000397115; CDR0000512740; 384;

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22/05/2025


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