Preferred Label : POU2F3 wt Allele;
NCIt synonyms : OTF-11; PLA1; OCT-11; POU Class 2 Homeobox 3 wt Allele; POU Domain Class 2, Transcription Factor 3 Gene; OCT11; OTF11; Epoc-1; POU Domain Transcription Factor OCT11a Gene; SKN1A; Skn-1a; POU Domain, Class 2, Transcription Factor 3 Gene; PLA-1;
NCIt definition : Human POU2F3 wild-type allele is located in the vicinity of 11q23.3 and is approximately
83 kb in length. This allele, which encodes POU domain, class 2, transcription factor
3 protein, plays a role in the promotion of cell proliferation and differentiation.
Aberrant promoter methylation of this gene may play a role in cervical cancer.;
NCIt note : Multiple transcript variants produced by alternative splicing have been described
for the POU2F3 gene. The gene produces at least three alternatively spliced isoforms,
the full-length transcript (SKN1A) and 2 other transcripts, which have different initiation
sites, with SKN1D1 and SKN1D2 initiating in introns 5 and 7, respectively. (OMIM);
NCI Metathesaurus CUI : CL1773928;
GenBank Accession Number : AF133895;
Origin ID : C185591;
UMLS CUI : C5575353;
Automatic exact mappings (from CISMeF team)
- OMIM relation
- Semantic type(s)
- gene_found_in_organism
- gene_in_chromosomal_location
- gene_plays_role_in_process
