Infant-Type Hemispheric Glioma, ALK-Altered

Preferred Label : Infant-Type Hemispheric Glioma, ALK-Altered;

NCIt definition : A high-grade cellular astrocytoma that arises in the cerebral hemisphere and occurs in early childhood. It is characterized by receptor tyrosine kinase fusions in the ALK gene.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1773776;

Details

Origin ID

C185474;

UMLS CUI

C5669922;

Disease may have findings
- Necrotic Change [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebral Hemisphere [NCIt concept]
- Nervous System [NCIt concept]
- Supratentorial Brain [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
disease_has_finding
- ALK Fusion Gene Positive [NCIt concept]
- Childhood Lesion [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]

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