Infant-Type Hemispheric Glioma

Preferred Label : Infant-Type Hemispheric Glioma;

NCIt definition : A high-grade cellular astrocytoma that arises in the cerebral hemisphere and occurs in early childhood. It is characterized by receptor tyrosine kinase fusions in the NTRK family, ROS1, ALK, or MET genes. It includes the following subtypes: infant-type hemispheric glioma, NTRK-altered, infant-type hemispheric glioma, ROS1-altered, infant-type hemispheric glioma, ALK-altered, and infant-type hemispheric glioma, MET-altered.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1773773;

Details

Origin ID

C185471;

UMLS CUI

C5669919;

Currated CISMeF NLP mapping
- Infant-type hemispheric glioma [ICD-11 Extension code]
Disease may have findings
- Necrotic Change [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebral Hemisphere [NCIt concept]
- Nervous System [NCIt concept]
- Supratentorial Brain [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Infant-type hemispheric glioma [MedDRA LLT]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
disease_has_finding
- Childhood Lesion [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]

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